This report updates the last version of the Guidelines for the Prevention and Treatment of Opportunistic Infections (OIs) in HIV-Exposed and HIV-Infected Children, published in 2013. These guidelines are intended for use by clinicians and other health-care workers providing medical care for children living with HIV (CLHIV) and children exposed to but not infected by HIV in the United States. The guidelines discuss opportunistic infections that occur in the United States and ones that might be acquired during international travel, such as malaria.
These guidelines are developed by a panel of specialists in pediatric HIV infection and infectious diseases from the U.S. government and academic institutions. Guidelines undergo further revision, with review and approval by the Panel, and final review and endorsement by the National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), the HIV Medicine Association (HIVMA) of the Infectious Diseases Society of America (IDSA), the Pediatric Infectious Disease Society (PIDS), and the American Academy of Pediatrics (AAP). Each section will be marked with the date of its last update. The Panel’s goal is to review each section for updates approximately every 2 years, with shorter intervals in response to availability of new treatments or relevant research findings.
The most important recommendations are highlighted in boxed major recommendations preceding each section, and a table of dosing recommendations appears at the end of each section. The guidelines conclude with summary tables that display dosing recommendations for all of the conditions, drug toxicities, and drug interactions, and figures summarizing immunization recommendations.
To view the guidelines, please click below: